![endorphin levels endorphin levels](https://els-jbs-prod-cdn.jbs.elsevierhealth.com/cms/attachment/6f43c565-278c-46e0-8e90-435667ab0632/gr5.jpg)
In our study serum beta-endorphin levels showed no significant difference between patients with painless diabetic peripheral neuropathy and those with painful diabetic peripheral neuropathy with different characters of pain. Serum beta-endorphin shows no significant difference between painful and painless neuropathy subgroups (p = 0.701).Ĭonclusion. While it was not correlated with pain severity (p = 0.371), NDS: total score (p = 0.803), BMI (p = 0.801), serum creatinine (p = 0.074) or DM duration (p = 0.607). Serum beta-endorphin shows negative correlation with age (p = 0.049) and HbA1c (p = 0.048).
![endorphin levels endorphin levels](https://slideplayer.com/15497089/93/images/slide_1.jpg)
Serum beta-endorphin shows no significant difference between diabetic neuropathic, diabetic non neuropathic and control groups (p = 0.275). For all subjects, levels of HbA1c, serum creatinine, total cholesterol, triglycerides, HDL and LDL as well as serum levels of beta-endorphin were measured. The study was a case control study including 88 participants 73 diabetics and 15 age and sex matched healthy subjects. Their effect through presynaptic binding.Īim was to study serum beta-endorphin levels in diabetic patients with and without diabetic peripheral neuropathyĪnd its relations to characters and severity of pain in patients with painful diabetic peripheral neuropathy. It also stimulates the production of endorphins, chemicals in the. Receptors (particularly of the mu subtype) at both preand post-synaptic nerve terminals, primarily exerting Exercise reduces levels of the bodys stress hormones, such as adrenaline and cortisol. Acupuncture apparently alleviates the awareness of pain. Myofascial pain is relieved primarily by inactivating the source of pain.
![endorphin levels endorphin levels](https://cdn-prod.medicalnewstoday.com/content/images/articles/320/320839/senior-person-swimming-in-pool.jpg)
In the peripheral nervous system (PNS), beta-endorphins produce analgesia by binding to opioid One experimentally well-documented mechanism for pain relief by acupuncture is the modulation of endorphin levels.